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KMID : 0365919930290080013
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Journal of the Pusan Medical Association
1993 Volume.29 No. 8 p.13 ~ p.18
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Two Cases of Histiocytic Necrotizing Lymphadenitis
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강경순
최경화/박광욱/이화모/전영석/이태원
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Abstract
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Histiocytic necrotizing lymphadenitis(HNL) or Kikuchi's disease is a newly recognized disease of unknown origin that causes cervical lymphadenitis, usually in young woman. It was first described in Japan in 1972 and has since been reported
throughout
the world.
Symptoms of HNL include tender cervical adenopathy, fever, weight loss, night sweats.
The origin of HNL is unknown and no specific diagnostic tests are available. Lymph node biopsy reveals areas with frank cellular necrosis, karyorrhexis and absence of plasma cell. The seats of histiocytes and immunoblasts may lead to misdiagnosis
of
large cell lymphoma or malignant histiocytosis. There fore diagnosis is estabilished on the basis of histopathologic studies, normal laboratory findings and self-limited clinical course. Only supportive treatment is necessary.
We experienced two cases of HNL and report with brief review of related liter-atures.
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KEYWORD
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